AHCC Selected Publications

Year PublishedTitleJournalMain category
(Disease / Part)
Lead authors , et al.
(Main Institution)
Link
2020Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirusMinerva Gastroenterologica e Dietologica, doi: 10.23736/S1121-421X.20.02697-5 (2020)Infection / Virus (Coronavirus)Francesco Di Pierro, Alexander Bertuccioli, Ilaria Cavecchia (Velleja Research)Read
2019From Bench to Bedside: Evaluation of AHCC Supplementation to Modulate the Host Immunity to Clear High-Risk Human Papillomavirus InfectionsFrontiers in Oncology, 9: 173 (2019)Infection / Virus (HPV)Judith A. Smith (UTHealth McGovern Medical School, USA), et al.Read
2019Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of Bifidobacterium longum, AHCC® and Azithromycin in Healthy IndividualsNutrients, 11(10), pii: E2470 (2019)Healthy PeopleAbeed H. Chowdhury, Miguel Cámara, Chandan Verma, Oleg Eremin, Anil D. Kulkarni and Dileep N. LoboRead
2019AHCC Supplementation Attenuates Muscle Atrophy via Akt Activation in Hindlimb-suspended RatBiotechnology and Bioprocess Engineering, 24: 476-482 (2019)Muscle AtrophyJeong-Beom Lee, et al. (Soonchunhyang University) Read
2019The Effects of AHCC®, a Standardized Extract of Cultured Lentinula edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal StudiesJournal of Immunology Research, Article ID 3758576 (2019)-Insoo Kang, et al. (Yale University School of Medicine)Read
2019A Pilot Open-Label Study Assessing the Effects of AHCC® Supplementation on Lyme Disease PatientsBioactive Compounds in Health and Disease, 2(11): 221-229 (2019)Infection / Bacteria ((Lyme Disease) Borrelia burgdorferi )John Salerno, Manami Misu, Eriko Ogawa, Jun Takanari (The Salerno Center for Complementary Medicine)Read
2019Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured Lentinula edodes myceliaJournal of Clinical Biochemistry and Nutrition, Article ID: 19-36 (2019)Cancer / ColonMaiko Takahashi, Gen Fujii, Takahiro Hamoya, Yurie Kurokawa, Yui Matsuzawa, Kohei Miki, Masami Koyama, Takumi Narita and Michihiro Mutoh (National Cancer Center Japan)Read
2019Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC® Natural Adjuvant against AspergillosisPharmaceutics, 11(9): 456 (2019)Infection / Fungus (Aspergillosis)Alba Pérez-Cantero, Dolores R. Serrano, Patricia Navarro-Rodríguez, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Juan J. Torrado and Javier Capilla (University Complutense)Read
2019Bioactive Immunomodulatory Compounds: A Novel Combinatorial Strategy for Integrated Medicine in Oncology? BAIC Exposure in Cancer CellsIntegrative Cancer Therapies, 18: 1534735419866908 (2019)Cancer / Breast, PancreaticBruna Corradetti, Salvatore Vaiasicca, Mauro Mantovani, Edy Virgili, Massimo Bonucci, and Ivano Hammarberg Ferri (Associazione Ricerca Terapie Oncologiche Integrate)Read
2019Active Hexose Correlated Compound has Protective Effects in Ischemia-Reperfusion Injury of the Rat Small IntestineJournal of Surgical Research, 243: 265-273 (2019)Inflammation / IntestineYosuke Ueyama, Katsuji Tokuhara, Hirokazu Miki, Richi Nakatake, Tatsuma Sakaguchi, Mikio Nishizawa, Masaki Kaibori and Tadayoshi Okumura (Kansai Medical University)Read
2019An open label trial of a standardized extract of cultured Lentinula edodes mycelia (ECLM) in children with refractory epilepsyFunctional Foods in Health and Disease, 9(3): 145-156 (2019)EpilepsyNatalia V. Mikhailichenko, Viacheslav Kulagin, Takuma Shio, Jun Takanari, James Cheng-Chung Wei (NEVRON International Medical Center)Read
2019Assessment of anti-inflammatory effects of Japanese Kampo medicine versus functional foodsFunctional Foods in Health and Disease, 9(2): 79-91 (2019)Inflammation / -Mikio Nishizawa, Tadayoshi Okumura, and Yukinobu Ikeya (Ritsumeikan University)Read
2018Active Hexose Correlated Compound (AHCC) Inhibits the Proliferation of Ovarian Cancer Cells by Suppressing Signal Transducer and Activator of Transcription 3 (STAT3) ActivationNutrition and Cancer, 70(1): 109-115 (2018)Cancer / OvarianJin Young Choi, Yong Beom Kim (Seoul National University Bundang Hospital, Korea), et al.Read
2018Clinical outcomes of active hexose correlated compound (AHCC®) and its effect on chemotherapy related adverse events in patients with unresectable pancreatic cancerDiagnosis, 83(3): 56-60 (2018)Cancer / PancreaticAnarkhuu Bold-Erdene, Amarbat Baatarnum, Zambalgarav Yadamjav, Chinburen Jidjidsuren (National Cancer Center of Mongolia)Read
2018CUB Domain-containing Protein 1 (CDCP1) Is Down-regulated by Active Hexose-correlated Compound in Human Pancreatic Cancer CellsAnticancer Research, 38(11): 6107-6111 (2018)Cancer / PancreaticKEISUKE KUHARA, KAZUHIRO TOKUDA, TAKAO KITAGAWA, BYRON BARON, MASAYUKI TOKUNAGA, KOJI HARADA, MASARU TERASAKI, OSAMU UEHARA, TOHRU OHTA, RIE TAKAI, JUN-ICHI HAMADA, MASANOBU KOBAYASHI,
TSUYOSHI SHIMO, HIROKI NAGAYASU, ASUHIRO KURAMITSU
Read
2018Screening for potential pathways of drug-supplement interactions between AHCC® and common medicationsInternational Journal of Nutritional Science and Food Technology, 4(5): 32-36 (2018)Cancer / LiverRachel E. Carlson, Anjali Gaikwad, Lata Mathew, Judith A.Smith (University of Texas Health Science Center Medical School)Read
2018Nutritional immunotherapy in autoimmune thyroid diseasesВЕСТНИК ЭНДОКРИНОПОГИИ(Bulletin of ENDOCRINOPOPHIA), 2(50): 23-27 (2018) (In Russian)Autoimmune Disease / Thyroid (incl. Graves disease)Zaure Zhaparkhanova, et al. (Kazakh National Medical University)Read
2018Effects of AHCC® on Immune and Stress Responses in Healthy IndividualsJournal of Evidence-Based Integrative Medicine, 23 (2018)Healthy People / StressJun Takanari, Atsuya Sato, Hideaki Waki, Shogo Miyazaki, Kazuo Uebaba and Tatsuya Hisajima (Teikyo Heisei University)Read
2017Evaluation of Active Hexose Correlated Compound (AHCC) in Combination With Anticancer Hormones in Orthotopic Breast Cancer ModelsIntegrative Cancer Therapies, 16(3): 300-307 (2017)Cancer / BreastJudith A. Smith (UTHealth-Memorial Hermann Cancer Center, USA), et al.Read
2017Long-term administration of Active Hexose Correlated Compound as a dietary supplement to a patient after breast cancer surgery and chemotherapy: A case reportIntegrative Cancer Science and Therapeutics, 4(1): DOI: 10.15761/ICST.1000226 (2017)Cancer / BreastKoji Wakame, Ken-ichi Komatsu (Hokkaido Pharmaceutical University School of Pharmacy, Japan), et al.
Read
2017The Effects of Active Hexose Correlated Compound (AHCC) on Levels of CD4+ and CD8+ in Patients with Epithelial Ovarian Cancer or Peritoneal Cancer Receiving Platinum Based ChemotherapyAsian Pacific Journal of Cancer Prevention, 18(3): 633-638 (2017)Cancer / Ovarian Wineeya Suknikhom, Ruangsak Lertkhachonsuk, Tarinee Manchana (Chulalongkorn University, Thailand)Read
2017MicroRNA signature in the chemoprevention of functionally-enriched stem and progenitor pools (FESPP) by Active Hexose Correlated Compound (AHCC)Cancer Biology & Therapy, 18(10): 765-774 (2017)Cancer / BreastÉmilie A. Graham, Jean-Fran¸cois Mallet, Majed Jambi, Hiroshi Nishioka, Kohei Homma, and Chantal Matara (University of Ottawa)Read
2017Active hexose-correlated compound enhances extrinsic-pathway-mediated apoptosis of Acute Myeloid Leukemic cellsPLOS ONE, 12(7): e0181729 (2017)Cancer / Leukemia Kavin Fatehchand, Ramasamy Santhanam, Brenda Shen, Ericka L. Erickson, Shalini Gautam, Saranya Elavazhagan, Xiaokui Mo, Tesfaye Belay, Susheela Tridandapani, Jonathan P. Butchar (The Ohio State University)Read
2017The Effects of Active Hexose Correlated Compound (AHCC) on Levels of CD4+ and CD8+ in Patients with Epithelial Ovarian Cancer or Peritoneal Cancer Receiving Platinum Based ChemotherapyAsian Pacific Journal of Cancer Prevention, 18(3): 633-638 (2017)Cancer / OvarianWineeya Suknikhom, Ruangsak Lertkhachonsuk, Tarinee Manchana (Chulalongkorn University)Read
2016Alleviating effect of Active Hexose Correlated Compound (AHCC) on chemotherapy-related adverse events in patients with unresectable pancreatic ductal adenocarcinomaNutrition and Cancer, 68(2): 234-240 (2016)Cancer / PancreaticYanagimoto H (Kansai Medical University) et al. Read
2016DNA microarray analysis of gene expression changes in ICR mouse liver following treatment with active hexose correlated compoundIntegrative Molecular Medicine, 3(3): 739-744 (2016)Inflammation / LiverKoji Wakame, Ken-ichi Komatsu (Hokkaido Pharmaceutical University School of Pharmacy, Japan), et al.Read
2016Protective effects of active hexose correlated compound in a rat model of liver injury after hepatectomyFunctional Foods in Health and Disease, 6(11): 702-717 (2016)Inflammation / LiverRichi Nakatake, Masanori Kon (Kansai Medical University, Japan), et al.Read
2016Active hexose correlated compound modulates LPS-induced hypotension and gut injury in ratsInternational Immunopharmacology, 39: 280-286 (2016)Colitis / IntestineMarie-Francoise Doursout, Yangyan Liang, Alamelu Sundaresan, KojiWakame, Hajime Fujii, Jun Takanari, Sundar Devakottai, Anil Kulkarni (The University of Texas Health Science Center at Houston)Read
2016Polysaccharide from Lentinus edodes for Integrative Cancer Treatment: Immunomodulatory Effects on Lymphocyte PopulationWorld Cancer Research Journal, 3(1): e652 (2016)Cancer / -A. DEL BUONO, M. BONUCCI, S. PUGLIESE, A. D’ORTA, M. FIORANELLI (Casa di Cura San Feliciano)Read
2015Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-being miceNutrition Research and Practice, 9(2): 129-136, (2015)Cancer / LiverZhiyun Cao, Lianming Liao (Fujian University of traditional Chinese Medicine, China), et al.Read
2015Active Hexose Correlated Compound (AHCC) promotes an intestinal immune response in BALB/c mice and in primary intestinal epithelial cell culture involving toll-like receptors TLR-2 and TLR-4European Journal of Nutrition, 55(1): 139-146 (2015)- / IntestineJ.-F. Mallet, Barry W. Ritz, Chantal Matar (University of Ottawa, Canada), et al.Read
2015Effects of Active Hexose Correlated Compound on the Seasonal Variations of Immune Competence in Healthy SubjectsJournal of Evidence-Based Complementary & Alternative Medicine, 20(1): 28-34 (2015)Healthy PeopleJun Takanari, Takahiro Maeda (Amino Up Chemical Co, Ltd, Japan), et al.Read
2015Attenuation of Pulmonary Mycobacterium Avium Disease by Active Hexose Correlated Compound (AHCC) in MiceJournal of Nutritional Disorders & Therapy, 5(4) (2015)Infection / Bacteria (Mycobacterium avium)Masaki Fujita, Takemasa Matsumoto, Ryosuke Hirano, Kazunari Ishii, Kenji Hiromatsu, Junji Uchino and Kentaro Watanabe (Fukuoka University)Read
2015AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell ActivationEvidence-Based Complementary and Alternative Medicine, Article ID 508746 (2015)-Loretta Olamigoke, Elvedina Mansoor, VivekMann, Ivory Ellis, Elvis Okoro, Koji Wakame, Hajime Fuji, Anil Kulkarni, Marie Francoise Doursout, and Alamelu Sundaresan (The University of Texas Medical School)Read
2015Active Hexose Correlated Compound and T Cell Response in Hind - Limb - Unloaded BALB/c MiceInternational Journal of Surgery and Research, 2(5): 32-38 (2015)-Kogiso M, Wakame K, Sakai T, Yamamoto S, Sundaresan A, Kulkarni AD (The University of Texas Health Science Center at Houston)Read
2015Active Hexose-correlated Compound Down-regulates Heat Shock Factor 1, a Transcription Factor for HSP27, in Gemcitabine-resistant Human Pancreatic Cancer CellsAnticancer Research, 35(11), 6063-6067 (2015)Cancer / Pancreatic MASAYUKI TOKUNAGA, BYRON BARON, TAKAO KITAGAWA, KAZUHIRO TOKUDA and YASUHIRO KURAMITUS (Yamaguchi University)Read
2015Therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with CpG-ODN (oligodeoxynucleotide) in B16 melanoma murine modelCytokine, 76(2): 131-137 (2015)Cancer / Skin (Melanoma)Rosa Mistica Ignacio, Cheol-Su Kim, Young-Do Kim, Hak-Min Lee, Xu-Feng Qi, Soo-Ki Kim (Yonsei University)Read
2015Active Hexose Correlated Compound Activates Immune Function to Decrease Chlamydia trachomatis Shedding in a Murine Stress ModelJournal of Nutritional Medicine and Diet Care, 1(1) (2015)Infection / Bacteria (Chlamydia trachomatis)Tesfaye Belay, Chuh-lung and Anthony Woart (National Institute of Allergy and Infectious Diseases)Read
2015Evaluation of active hexose correlated compound (AHCC) on phase II drug metabolism pathways and the implications for supplement-drug interactionsJournal of Integrative Oncology, DOI:10.4172/2329-6771.1000142 (2015)Inflammation / LiverLarry W Coffer, Lata Mathew, Xue Zhang, Norah A. Owiti, Alan L Myers, Jonathan Faro and Judith A Smith (University of Texas Health Science Center Medical School at Houston)Read
2014Reduction of Adverse Effects by a Mushroom Product, Active Hexose Correlated Compound (AHCC) in Patients with Advanced Cancer during Chemotherapy-The Significance of the Levels of HHV-6 DNA in Saliva as a Surrogate Biomarker during ChemotherapyNutrition and Cancer, 66(3): 377-382 (2014)Cancer / BreastToshinori Ito, Hatsumi Honda (Osaka University Graduate School of Medicine, Japan), et al.Read
2014Effect of Active Hexose Correlated Compound (AHCC) in Alcohol-Induced Liver Enzyme ElevationJournal of Nutritional Science and Vitaminology, 60(5): 348-356 (2014)Inflammation / LiverJung-Ha Kim (Chung-Ang University College of Medicine, Korea), Jee-Aee Im (Sports and Medicine Research Center, Korea)Read
2014Adenosine, a hepato-protective component in active hexose correlated compound: Its identification and iNOS suppression mechanismNitric Oxide, 40: 75-86 (2014)Inflammation / LiverYoshito Tanaka, A-Hon Kwon (Kansai Medical University, Osaka, Japan), et al.Read
2014Active hexose correlated compound exerts therapeutic effects in lymphocyte driven colitisMolecular Nutrition & Food Research, 58(12): 2379-2382 (2014)Colitis / IntestineCristina Mascaraque, Olga Martínez-Augustin (University of Granada, Spain), et al.Read
2014Active Hexose-correlated Compound Down-regulates Sex-determining Region Y-box 2 of Pancreatic Cancer CellsAnticancer Research, 34(9): 4807-4811 (2014)Cancer / Pancreatic JUNYA NAWATA, YASUHIRO KURAMITSU, YUFENG WANG, TAKAO KITAGAWA, KAZUHIRO TOKUDA, BYRON BARON, JUNKO AKADA, SHIGEYUKI SUENAGA, SEIJI KAINO, SHIN-ICHIRO MAEHARA, YOSHIHIKO MAEHARA, ISAO SAKAIDA and KAZUYUKI NAKAMURA ( Health Sciences University of Hokkaido, Yamaguchi University)Read
2014Active Hexose-correlated Compound Down-regulates HSP27 of Pancreatic Cancer Cells, and Helps the Cytotoxic Effect of GemcitabineAnticancer Research, 34(1): 141-146 (2014)Cancer / Pancreatic SHIGEYUKI SUENAGA, YASUHIRO KURAMITSU, SEIJI KAINO, SHIN-ICHIRO MAEHARA, YOSHIHIKO MAEHARA, ISAO SAKAIDA and KAZUYUKI NAKAMURA (Yamaguchi University)Read
2013Effect of Active Hexose-Correlated Compound in Women Receiving Adjuvant Chemotherapy for Breast Cancer: A Retrospective StudyThe Journal of Alternative and Complementary Medicine, 19(11): 905-910 (2013)Cancer / BreastSho Hangai (The University of Tokyo Hospital, Japan), Satoru Iwase (The University of Tokyo, Japan), et a.Read
2013Short-term supplementation with active hexose correlated compound improves the antibody response to influenza B vaccineNutrition Research,33(1),12-17Infection / Virus (Influenza B)Brooke E. Roman, Elizabeth M. Gardner, et al. (Michigan State University, USA)Read
2013A natural immune modulator attenuates stress hormone and catecholamine concentrations in polymicrobial peritonitisThe Journal of Trauma and Acute Care Surgery, 74(6): 1411-1418 (2013)- / StressKatie M. Love, William G. Cheadle (School of Medicine, University of Louisville, USA), et al.Read
2013Active hexose-correlated compound and Bifidobacterium longum BB536 exert symbiotic effects in experimental colitisEuropean Journal of Nutrition, 52(2): 457-466 (2013)Colitis / IntestineBorja Oco´n, Andrea Anzola, Mercedes Ortega-Gonza´lez, Antonio Zarzuelo, Marı´a D. Sua´rez, Fermı´n Sa´nchez de Medina, Olga Martı´nez-Augustin (University of Granada)Read
2013Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.Life Science, 93(25-26): 994-1003 (2013)Cancer / BreastMehran Haidari, Wei Zhang, Koji Wakame (The University of Texas Health Science Center at Houston)Read
2013An Evidence-Based Systematic Review of Active Hexose Correlated Compound (AHCC) by the Natural Standard Research CollaborationJournal of Dietary Supplements, 10(3): 264-308 (2013)-Catherine Ulbricht, Ashley Brigham, J. Kathryn Bryan, Marisa Catapang, Divya Chowdary, Dawn Costa, Samantha Culwell, Denise D’Auria, Nicole Giese, Ramon Iovin, Richard Isaac, Vijaya Juturu, Angela Liu, Meredith Mintzer, Erica Rusie, Michael Shaffer and Regina C. Windsor (Natural Standard Research Collaboration)Read
2013Active Hexose Correlated Compound Extends the Lifespan and Increases the Thermotolerance of NematodesFunctional Foods in Health and Disease, 3(6):166-182 (2013)-Tetsuya Okuyama, Emi Yoshigai, Yukinobu Ikeya, and Mikio Nishizawa (Ritsumeikan University)Read
2013The nutritional supplement Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-κB/MAPK activationFood Chemistry, 136(3-4): 1288-1295 (2013)- / IntestineAbdelali Daddaoua, Enrique Martínez-Plata, Mercedes Ortega-González, Borja Ocón d, Carlos J. Aranda, Antonio Zarzuelo, María D. Suárez, Fermín Sánchez de Medina, Olga Martínez-Augustin (University of Granada)Read
2013Stabilization of human interferon-α1 mRNA by its antisense RNACellular and Molecular Life Sciences, 70(8): 1451-1467 (2013)-Tominori Kimura, Shiwen Jiang, Mikio Nishizawa, Emi Yoshigai, Iwao Hashimoto, Masao Nishikawa, Tadayoshi Okumura, Hisao Yamada (Ritsumeikan University)Read
2012Active Hexose Correlated Compound (AHCC) Alleviates Gemcitabine-Induced Hematological Toxicity in Non-Tumor-Bearing MiceInternational Journal of Clinical Medicine, 3: 361-367 (2012)Cancer / -Daisuke Nakamoto, Hiroshi Nishioka (Amino Up Chemical Co., Ltd., Japan), et al., Read
2012Active Hexose Correlated Compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1β production from monocytes in humansCellular Immunology, 275(1-2): 19-23 (2012)-Won-Woo Lee, Naeun Lee, Hajime Fujii, Insoo Kang (Yale University School of Medicine)Read
2012Personalized Cancer Therapy for Stage IV Lung Cancer: Combined Use of Active Hexose Correlated Compound and Genistein Concentrated PolysaccharidePersonalized Medicine Universe, 1(1): 39-44 (2012)Cancer / LungReiki Ishizuka, Kuniyoshi Tajima, et al. (Tajima Clinic)Read
2012Immunoprophylactic Effect of Active Hexose Correlated Compound on Normal and Induced Submandibular Salivary Gland Neoplasm in Albino RatsCairo Dental Journal, 28(1): 485-490 (2012)Cancer / Salivary GlandTamer A. Badawi, Nahed A. Khalil, Amal H. Abdelrahman and Zouba H. Aly (Cairo University)Read
2011Evaluation of active hexose correlated compound (AHCC) in combination with pegylated liposomal doxorubicin for treatment of ovarian cancerInternational Journal of Applied Research in Natural Products, 4(3): 6-14 (2011)Cancer / OvarianJudith A. Smith (UTHealth-Memorial Hermann Cancer Center, USA), et al.Read
2011Active Hexose Correlated Compound Inhibits the Expression of Proinflammatory Biomarker iNOS in HepatocytesEuropean Surgical Research, 47: 274-283 (2011)Inflammation / LiverK. Matsui, T. Okumura, et al. (Kansai Medical University, Japan)Read
2011An Evidence-Based Review of a Lentinula edodes Mushroom Extract as Complementary Therapy in the Surgical Oncology PatientJournal of Parenteral and Enteral Nutrition, 35(4): 449-458 (2011)Cancer / VariousShinil K. Shah, Peter A. Walker, Stacey D. Moore-Olufemi, Alamelu Sundaresan, Anil D. Kulkarni (University of Texas Medical School at Houston)
and Richard J. Andrassy,
Read
2011Integrating Complimentary and Alternative Medicine in Form of Active Hexose Correlated Compound (AHCC) in the Management of Head & Neck Cancer PatientsInternational Journal of Clinical Medicine, 2, 588-592 (2011)Cancer / Head & NeckDillip Kumar Parida, Koji Wakame, Taisei Nomura (North Eastern Indira Gandhi Regional Institute of Health & Medical Sciences)Read
2011Diet and prostate cancer - a holistic approach to managementArchivos Españoles de Urologia, 64(8): 720-735 (2011)Cancer / Prostate Philippa J Cheetham and Aaron E Katz (Columbia University Medical Center)Read
2011Genotoxicity and subchronic toxicity evaluation of Active Hexose Correlated Compound (AHCC)Regulatory Toxicology and Pharmacology, 59(2): 237-250 (2011)-H. Fujii, N. Nishioka, R.R. Simon, R. Kaur, B. Lynch, A. Roberts (Cantox Health Sciences International)Read
2011Active Hexose Correlated Compound (AHCC) and Immune Outcomes in Humans: A ReviewNatural Medicine Journal, 3(1): 3-7 (2011)-Barry W. Ritz (Atrium Innovations, Inc.)Read
2010Effects of active hexose correlated compound on frequency of CD4+and CD8+T cells producing interferon-γ and/or tumor necrosis factor-α_x0002_in healthy adultsHuman Immuology,71,1187-1190Healthy PeopleZhinan Yin, Thomas Walshe, et al. (Brigham and Women's Hospital and Harvard Medical School, USA)Read
2010A study of the efficacy of Active Hexose Correlated Compound (AHCC) in the treatment of chronic Hepatitis C patients at Phramongkutklao HospitalThe Medical News (In Thai)Infection / Virus (Hepatitis C)Sayam Thaiudom, Anuchit Chutaputthi, et al. (Phramongkutklao Hospital, Thailand)Read
2010Dietary Administration of Mushroom Mycelium Extracts in Patients with Early Stage Prostate Cancers Managed Expectantly: A Phase II StudyJpn. J. Clin. Oncol.,40(10),967-972Cancer / Prostate Y. Sumiyoshi et al. (Shikoku Cancer Center), Nobuo Shinohara (Hokkaido University School of Medicine), et al.Read
2010Review of Cancer Therapy with AHCC(R) and GCP(R); The Long-Term Follow-Up over 12 Years for Stage IV (M1) Cancer of the Lung and the BreastInternational Journal of Integrative Medicine 2(1): 98-111 (2010)Cancer / Lung, BreastReiki Ishizuka, Kuniyoshi Tajima, et al. Read
2010Basic and Clinical Studies on Active Hexose Correlated CompoundBiotechnology in Functional Foods and Nutraceuticals (Taylor & Francis)-Takehito Miura, Kentaro Kitadate, Hiroshi Nishioka, and Koji Wakame (Amino Up)Read
2009Oral Administration of Active Hexose Correlated Compound Enhances Host Resistance to West Nile Encephalitis in Mice.Journal of Nutrition,139,598-602Infection / Virus (West Nile Virus)Zhinan Yin, Thomas Walshe, et al. (Brigham and Women's Hospital and Harvard Medical School, USA)Read
2009The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodentsCancer Epidemiology,33,293-299- / LiverBuxiang Sun (Amino Up Chemical Co., Ltd.), Okezie I. Aruoma (Touro College of Pharmacy, USA) et al.Read
2009Alleviating effect of active hexose correlated compound (AHCC) for anticancer drug-induced side effects in non-tumor-bearing miceExp. Therap. & Oncol.,8(1),43-51Cancer / -Kota Shigama, Hajime Fujii, et al. (Amino Up Chemical, Co., Ltd.) Read
2008Immunological Effect of Active Hexose Correlated Compound (AHCC) in Healthy Volunteers: A Double-Blind, Placebo-Controlled TrialNutrition and Cancer, 60(5): 643-651Healthy PeopleNaoyoshi Terakawa, Yasuo Kamiyama, et al. (Kansai Medical University, Japan)Read
2008Evaluation of Active Hexose Correlated Compound Hepatic Metabolism and Potential for Drug Interactions with Chemotherapy AgentsJournal of the Society for Integrative Oncology, 6(3): 105-109 (2008)Cancer / LiverClaire M. Mach, Judith Smith (The University of Texas M. D. Anderson Cancer Center), et al.Read
2007The influence of active hexose correlated compound (AHCC) on cisplatin-evoked chemotherapeutic and side effects in tumor-bearing miceToxicol. Appl. Pharmacol.,222,152-158Cancer / ColonAya Hirose (Amino Up Chemical, Co., Ltd.) Okezie I. Aruoma (Touro College of Pharmacy, USA), et al.Read
2007Active Hexose Correlated Compound Acts as a Prebiotic and Is Antiinflammatory in Rats with Hapten-Induced Colitis.Journal of Nutrition,137,1222-1228Colitis / IntestineAbdelali Daddaoua, Olga Martinez-Augustin (University of Granada, Spain), et al.Read
2007Effect of active hexose correlated compound on the production of nitric oxide in hepatocytesJournal of Parenteral and Enteral Nutrition, 31(5): 373-381 (2007)Inflammation / LiverK. Matsui, Nishizawa, et al. (Kansai Medical University, Japan)Read
2006Prognostic Improvement of Patients with Advanced Liver Cancer after AHCC TreatmentAsian Pacific Journal of Allergy and Immunology, 24(1): 33-45 (2006)Cancer / LiverSuwanna Cowawintaweewat, Wanpen Chaicumpa (Thammasat University, Thailand), et al.Read
2002Improved prognosis of postoperative hepatocellular carcinoma patients when treated with functional foods: a prospective cohort studyJournal of Hepatology,37,78-86Cancer / LiverY. Matsui, et al. (Kansai Medical University)Read
2000Propylactic Efficacy of a Basidiomycetes Preparation AHCC against Lethal Opportunistic Infections in MiceYAKUGAKU ZASSHI,120(8),715-719Infection / Bacteria (Lethal Opportunistic)Hiroko Ishibashi, Shigeru Abe, et al.(Teikyo University School of Medicine)Read
1998Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinomaAnti-Cancer Drugs, 9(4): 343-350 (1998)Cancer / BreastKazuhiro Matsusita, Masuo Hosokawa, et al. (Hokkaido University School of Medicine)Read